TMRP Doctoral Training Partnership

TMRP DTP Studentships

Applications for October 2024 are now open


Are you interested in medical research that matters to patients and the NHS?

The MRC-NIHR Trials Methodology Research Partnership (TMRP) aims to Improve health by improving trials. Our MRC Doctoral Training Partnership presents an opportunity to undertake training for a PhD in trials methodology.

We will advertise upcoming projects in various areas including statistics, data analytics and informatics, computer science, health economics, qualitative methods, mixed-methods, clinical medicine and psychology.


Professional development training and support

Students will become members of the TMRP, offering a broader spectrum of training activities and networking opportunities beyond their host Research Organisation. Students will be encouraged to join relevant TMRP working groups, where they will meet other PhD students, post-doctoral researchers and senior academic staff from relevant and complementary research themes. In addition to a structured ‘core’ training programme, we are able to provide a range of more specific training that students may choose to attend following consultation with their supervisors.

Our Associate Partner Research Organisations are able to offer opportunities for students that will include: research visits; internships with industry, regulatory bodies and clinical trials units; engagement with health professional and other research networks. We will encourage and support DTP students to apply for international internship schemes such as the UKRI UK-Canada Globalink Doctoral Exchange Scheme.

Below is the list of projects currently available.

For details on how to apply visit


University of Aberdeen

Extending the estimands framework to surgical trials: implications for design and analysis

Optimising the collection and use of health economic data within trials

Bangor University

Analysis decisions for non-negative continuous outcome data collected within RCTs

How should the environmental impact of a pharmaceutical intervention be considered in the context of trial outcomes

Institute of Cancer Research (ICR)

Asking the right questions in cancer clinical trials: Unlocking the potential of the estimand framework as a multi-disciplinary approach to trial development

Patient & public involvement (PPI) in the selection of trial endpoints in late phase adult cancer clinical trials

Newcastle University

Eliciting expert knowledge in the design and analysis of trials in rare diseases

Identifying and validating digital biomarkers of frailty in Parkinson’s disease

Use of artifical intelligence methods in the conduct and analysis of trials

Queen Mary University London (QMUL)

Investigating the feasibility of Decision Architecture Randomised Trials (DARTs) to address standard of care questions within UK primary care

Issues in cost–effectiveness analysis for multinational clinical trials

Pilot and feasibility studies for online clinical trials

Surrogate endpoints for cancer screening trials

University College London (UCL)

Increasing impact of non-industry drug clinical trials through experience with regulatory submission

Patient and Public Involvement in late-phase clinical trials testing multiple primary research questions

University of Birmingham

Exploring the broader costs and outcomes of public health interventions in low- and middle-income country (LMIC) settings, using a case study of a mother and community targeted behavioural intervention to improve complementary food safety, hygiene, nutrition, and improved safe child play practices in urban and rural Mali

Exploring the inequalities and power balances of Community Engagement and Involvement in Global Health Research

Stratified Trials and Experimental Medicine Studies exploring Transdiagnostic Approaches to Psychosis and Depression

University of Cambridge

Adaptive Designs for the evaluation of updates to algorithms and devices in digital healthcare

Adaptive methods for a complex endpoint: number of days alive at home

Designs for sequences of early phase (modular) studies

Developing randomisation guidance and resources for implementing optimal constrained 2-armed trial designs

Master protocol trials for the development of oncology drugs

Operationally feasible Multi-Arm-Bandit Response Adaptive Trials

University of Glasgow

Making trials more equity focused for minority ethnic people: Assessing differential treatment effectiveness and under-inclusion

Platform trials: role of simulation in design

University of Leeds

Defining standards for layered patient information in clinical research

Design and analysis of programmes of cluster-randomised trials: Master protocols for implementation laboratories

Leveraging progression free survival data in cancer trials

University of Liverpool

Improving core outcome set uptake in trials

Investigating multimorbidity in clinical trials

University of Plymouth

Developing and testing methods of engagement and inclusion in trials involving people with alcohol-related liver disease

Improving adverse event reporting in rehabilitation trials for people with Multiple Sclerosis

Longitudinal analysis to explore the long-term changes in Multiple Sclerosis (MS) patient reported outcome measures

Modelling multiple ordinal outcomes in clinical trials

Optimising participant recruitment and retention in studies investigating pregnancy-related pelvic girdle pain

Using dynamic website content in participant information sheets to increase accrual rates