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Workshop: Methods for Adjusting for Treatment Switches in Late-Stage Cancer Trials

This workshop was held on February 20, 2012 in London. View the workshop programme.

Summary

Workshop report: Methods for adjusting for treatment switches in late-stage cancer trials

Presentations

Click on the links below to view the slide presentations:

• Methods for handling treatment switching: rank-preserving structural nested failure time models, inverse-probability-of-censoring weighting, and marginal structural models
• Departure from treatment protocol in published RCTs: a review
• Methods for adjusting survival estimates in the presence of treatment crossover - Simulation studies - Part A
• Methods for adjusting survival estimates in the presence of treatment crossover - Simulation studies - Part B
• Methods for health economic models in metastatic cancer
• Adjusting the Crossover Effect in Survival Analysis Using a Rank Preserving Structural Failure Time Model: The Case of Sunitinib GIST Trial
• Treatment switches in cancer trials - problems, pitfalls and (no) solutions
• Dealing with treatment switches in cost-effectiveness analysis: the NICE experience - Part A
• Dealing with treatment switches in cost-effectiveness analysis: the NICE experience - Part B